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Rocío Escobar Conesa

Hospital de Cabueñes,  Gijón

Monday, 29 August 2016

ANTISYNTHETASE SYNDROME, A DIAGNOSTIC CHALLENGE

Written by Jose Luis García de Veas Silva | Rocio Escobar Conesa | Maria del Señor Lopez Vélez, Posted in Volumen 3

SÍNDROME ANTI - SINTETASA, UN DESAFIO  DIAGNOSTICO
The attached image (Figure 1) corresponds to a dense fine speckled cytoplasmic pattern with neg a- tive metaphases at 1:640 observed by indirect imm u- nofluorescence (IIF) in Hep - 2 cells line. Suspecting the possible association with antisynthetase antib o- dies, the presence of antibodies anti PL - 7 and anti Ro - 52 kD (Figure 2) were identified by “myositis immunoblot”