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Vanessa García Moreira

Servicio de Análisis Clínicos, Hospital de Cabueñes, Gijón

Thursday, 28 April 2016

ANTI SS/RO AND ANTI SSB/LA IN A PATIENT WITH SJÖGREN SYNDROME

Written by Vanessa García Moreira | Angélica Cienfuegos González | Carlos Blanco Cristóbal, Posted in Volumen 2

ANTICUERPOS ANTI-SSA/RO Y ANTI-SSB/LA EN PACIENTE CON SÍNDROME DE SJÖGREN
Pictures 1 and 2 show a well of a plate indirect immunofluorescence (IIF) of Hep-2000® cells with a 1/2560 speckled pattern corresponding to anti-SSA/Ro (Ro60+Ro52) and anti-SSB/La antibody (lat-er demonstrated by immunoblotting in the picture 3).

Hep-2000® cells are squamous cell carcinoma of human esophagus which have been transfected with cDNA encoding the antigen SSA/Ro 60 KDa, thus conferring greater antigenic expression that increases specificity and sensitivity for the determination of these autoantibodies.